2026

The Sigma-1 Receptor Agonist Fluvoxamine Alleviates Endotoxin-induced Acute Lung Injury in Mice. Emese Ritter, Kata Csekő, Ádám Hosszú, Ákos R Tóth, Dóra Hargitai, László Kereskai, Andrea Fekete, Zsuzsanna Helyes. Front Pharmacol. 2026 Apr 28:17:1818198. https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2026.1818198/full

2026

The Sigma-1 Receptor Agonist Fluvoxamine Is Protective in Hyperglycaemia-Induced Dysfunction of Trabecular Meshwork Cells. Alexandra Rozsahegyi, Marcell Cserhalmi, Timea Medveczki, Zsuzsanna Buzogany, Eva Ruisanchez, Andras Budai, Balazs Besztercei, Attila J Szabo, Judit Hodrea, Andrea Fekete. Pharmaceuticals 2026, 19, 385.
https://www.mdpi.com/1424-8247/19/3/385

2025

Novel Sigma-1 receptor agonist alleviates renal ischemic injury by targeting apoptotic and inflammatory pathways.  Akos R Toth, Tamas Lakat, Andras Budai, Hanga Kallay, Balint Szokol, Laszlo J Wagner, Laszlo Orfi, Marcell Kreko, Attila J Szabo, Andrea Fekete, Adam Hosszu. Sci Rep. 2025 Nov 13;15(1):39762. https://www.nature.com/articles/s41598-025-23459-0

2024

Sigma-1 Receptor as a Novel Therapeutic Target in Diabetic Kidney Disease
Dora B. Balogh, Judit Hodrea, Adar Saeed, Marcell Cserhalmi, Alexandra Rozsahegyi, Tamas Lakat, Lilla Lenart, Attila J. Szabo, Laszlo J. Wagner, Andrea Fekete
International Journal of Molecular Sciences 2024, 25(24), 13327 
https://www.mdpi.com/1422-0067/25/24/13327

2023

The Sigma-1 Receptor Is a Novel Target for Improving Cold Preservation in Rodent Kidney Transplants
Adam Hosszu, Akos R. Toth, Tamas Lakat, Ganna Stepanova, Zsuzsanna Antal, Laszlo J. Wagner, Attila J. Szabo, Andrea Fekete
International Journal of Molecular Sciences 2023, 24, 11630
https://www.mdpi.com/1422-0067/24/14/11630

2023

Sigma-1 Receptor Agonist Fluvoxamine Ameliorates Fibrotic Response of Trabecular Meshwork Cells
Judit Hodrea, Minh Ngoc Tran, Balazs Besztercei, Timea Medveczki,  Attila J. Szabo, Laszlo Orfi, Illes Kovacs, Andrea Fekete
International Journal of Molecular Sciences 2023, 24, 11646
https://www.mdpi.com/1422-0067/24/14/11646

2023

Sigma-1 Receptor Activation Is Protective against TGFβ2-Induced Extracellular Matrix Changes in Human Trabecular Meshwork Cells
Minh Ngoc Tran, Timea Medveczki, Balazs Besztercei, Gyorgy Torok, Attila J. Szabo, Xavier Gasull, Illes Kovacs, Andrea Fekete, Judit Hodrea
Life 2023, 13, 1581
https://www.mdpi.com/2075-1729/13/7/1581

2019

Compositions for organ preservation
Andrea Fekete, Adam Vannay, Adam Hosszu
Patent EP3544420A1
https://patents.google.com/patent/EP3544420A1/en

2019

Novel use of sigma-1 receptor agonist compounds
Andrea Fekete, Adam Vannay, Endre Illes Kovacs, Judit Kis (Hodrea)*
Patent US20190209575A1
https://patents.google.com/patent/US20190209575A1/en

2018

The role of Sigma-1 receptor in sex-specific heat shock response in an experimental rat model of renal ischaemia/reperfusion injury
Adam Hosszu, Zsuzsanna Antal, Apor Veres-Szekely, Lilla Lenart, Dora B. Balogh, Edgar Szkibinszkij, Lilla Illesy, Judit Hodrea, Nora F Banki, Laszlo Wagner, Adam Vannay, Attila J. Szabo, Andrea Fekete
Transplant International, 2018
https://www.ncbi.nlm.nih.gov/pubmed/29908082

2017

σ1-Receptor Agonism Protects against Renal Ischemia-Reperfusion Injury
Adam Hosszu, Zsuzsanna Antal, Lilla Lenart, Judit Hodrea, Sandor Koszegi, Dora B. Balogh, Nora F. Banki, Laszlo Wagner, Adam Denes, Peter Hamar, Peter Degrell, Adam Vannay, Attila J Szabo, Andrea Fekete
Journal of the American Society of Nephrology, 2017
https://www.ncbi.nlm.nih.gov/pubmed/27056295

2016

The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats
Lilla Lenart, Judit Hodrea, Adam Hosszu, Sandor Koszegi, Dora Zelena, Dora B. Balogh, Edgar Szkibinszkij, Apor Veres-Szekely, Laszlo Wagner, Adam Vannay, Attila J. Szabo, Andrea Fekete
Psychopharmacology, 2016
https://www.ncbi.nlm.nih.gov/pubmed/26809458

2015

Novel use of sigma-1 receptor agonist compound
Andrea Fekete, Adam Vannay
hhttps://patents.google.com/patent/WO2015118365A1/en

*under registration